Articles

The list below contains peer-reviewed journal articles to which we contributed.

2019

176 Diabetic nephropathy alters the distribution of circulating angiogenic microRNAs among extracellular vesicles, HDL, and Ago-2 (pdf, 2 MB)
B.W. Florijn, J.M.G.J. Duijs, J.H. Levels, G.M. Dallinga-Thie, Y. Wang, A.N. Boing, Y. Yuana, W. Stam, R.W.A.L. Limpens, Y.W. Au, R. Nieuwland, T.J. Rabelink, M.E.J. Reinders, A.J. van Zonneveld, and R. Bijkerk
Diabetes 68 (12), 2287-2300 (2019)
175 Extracellular vesicles and coagulation in blood from healthy humans revisited (pdf, 2 MB)
René J. Berckmans, Romaric Lacroix, Chi M. Hau, Auguste Sturk, and Rienk Nieuwland
Journal of Extracellular Vesicles 8 (1), 1688936 (2019)
174 Clearance and phenotype of extracellular vesicles after red blood cell transfusion in a human endotoxemia model (pdf, 1 MB)
Lisa van Manen, Anna L. Peters, P. Matthijs van der Sluijs, Rienk Nieuwland, Robin van Bruggen, and Nicole P. Juffermans
Transfusion and Apheresis Science 58 (4), 508-511 (2019)
173 Toward standardization of assays measuring extracellular vesicle-associated tissue factor activity (pdf, <1 MB)
Rienk Nieuwland, Chris Gardiner, Françoise Dignat-George, François Mullier, Nigel Mackman, Barry Woodhams, and Johannes Thaler
Journal of Thrombosis and Haemostasis 17 (8), 1261-1264 (2019)
172 Embryology, anatomy, physiology and pathophysiology of the peritoneum and the peritoneal vasculature (pdf, 2 MB)
Arnoud W. Kastelein, Laura M.C. Vos, Kees H. de Jong, Juliette O.A.M. van Baal, Rienk Nieuwland, Cornelis J.F. van Noorden, Jan-Paul W.R. Roovers, and Christianne A.R. Lok
Seminars in Cell & Developmental Biology 92 (2019), 27-36 (2019)
171 Glycan-modified apoptotic melanoma-derived extracellular vesicles as antigen source for anti-tumor vaccination (pdf, 2 MB)
Sophie K. Horrevorts, Dorian A. Stolk, Rieneke van de Ven, Myrthe Hulst, Bert van het Hof, Sanne Duinkerken, Marieke H. Heineke, Wenbin Ma, Sophie A. Dusoswa, Rienk Nieuwland, Juan J. Garcia-Vallejo, Arjan A. van de Loosdrecht, Tanja D. de Gruijl, Sandra J. van Vliet, and Yvette van Kooyk
Cancers 11 (9), 1266 (2019)
170 Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells (pdf, 2 MB)
Sophie A. Dusoswa, Sophie K. Horrevorts, Martino Ambrosini, Hakan Kalay, Nanne J. Paauw, Rienk Nieuwland, Michiel D. Pegtel, Tom Würdinger, Yvette Van Kooyk, and Juan J. Garcia-Vallejo
Journal of Extracellular Vesicles 8 (1), 1648995 (2019)
169 Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles (pdf, 2 MB)
Aled Clayton, Eric Boilard, Edit I. Buzas, Lesley Cheng, Juan Manual Falcón-Perez, Chris Gardiner, Dakota Gustafson, Alice Gualerzi, An Hendrix, Andrew Hoffman, Jennifer Jones, Cecilia Lässer, Charlotte Lawson, Metka Lenassi, Irina Nazarenko, Lorraine O'Driscoll, Ryan Pink, Pia R.M. Siljander, Carolina Soekmadji, Marca Wauben, Joshua A. Welsh, Ken Witwer, Lei Zheng, and Rienk Nieuwland
Journal of Extracellular Vesicles 8 (1), 1647027 (2019)
168 The P4-ATPase ATP9A is a novel determinant of exosome release (pdf, 2 MB)
Jyoti Naik, Chi M. Hau, Lysbeth ten Bloemendaal, Kam S. Mok, Najat Hajji, Ann M. Wehman, Sander Meisner, Vanesa Muncan, Nanne J. Paauw, H.E. de Vries, R. Nieuwland, Coen C. Paulusma, and Piter J. Bosma
Plos One 14 (4), e0213069 (2019)
167 Clinical requirements for extracellular vesicle assays (pdf, 1 MB)
Lisa Ayers, Ryan Pink, David R.F. Carter, and Rienk Nieuwland
Journal of Extracellular Vesicles 8 (1), 1593755 (2019)
166 Quality of extracellular vesicle images by transmission electron microscopy is operator and protocol dependent (pdf, 2 MB)
L.G. Rikkert, R. Nieuwland, L.W.M.M. Terstappen, and F.A.W. Coumans
Journal of Extracellular Vesicles 8 (1), 1555419 (2019)
165 P2Y12 antagonist ticagrelor inhibits the release of procoagulant extracellular vesicles from activated platelets (pdf, 1 MB)
Aleksandra Gasecka, Rienk Nieuwland, Edwin van der Pol, Najat Hajji, Agata Ćwiek, Kinga Pluta, Michał Konwerski, and Krzysztof J. Filipiak
Cardiology Journal 26 (6), 782-9 (2019)
164 Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (pdf, 44 MB)
Andrea Cossarizza, Hyun-Dong Chang, Andreas Radbruch, Andreas Acs, Dieter Adam, Sabine Adam-Klages, William W. Agace, Nima Aghaeepour, Mübeccel Akdis, Matthieu Allez, Larissa Nogueira Almeida, Giorgia Alvisi, Graham Anderson, Immanuel Andrä, Francesco Annunziato, Achille Anselmo, Petra Bacher, Cosima T. Baldari, Sudipto Bari, Vincenzo Barnaba, Joana Barros-Martins, Luca Battistini, Wolfgang Bauer, Sabine Baumgart, Nicole Baumgarth et al.
European Journal of Immunology 49 (10), 1457-973 (2019)
163 Refractive index to evaluate staining specificity of extracellular vesicles by flow cytometry (pdf, 2 MB)
Leonie de Rond, Sten F.W.M. Libregts, Linda G. Rikkert, Chi M. Hau, Edwin van der Pol, Rienk Nieuwland, Ton G. van Leeuwen, and Frank A.W. Coumans
Journal of Extracellular Vesicles 8, 1643671 (2019)
162 Proteomics characterization of extracellular vesicles sorted by flow cytometry reveals a disease-specific molecular cross-talk from cerebrospinal fluid and tears in multiple sclerosis (pdf, 3 MB)
Damiana Pieragostino, Paola Lanuti, Ilaria Cicalini, Maria Concetta Cufaro, Fausta Ciccocioppo, Maurizio Ronci, Pasquale Simeone, Marco Onofrj, Edwin van der Pol, Antonella Fontana, Marco Marchisiob, and Marco Del Boccio
Journal of Proteomics 204, 103403 (2019)
161 The generation and use of recombinant extracellular vesicles as biological reference material (pdf, 3 MB)
Edward Geeurickx, Joeri Tulkens, Bert Dhondt, Jan Van Deun, Lien Lippens, Glenn Vergauwen, Elisa Heyrman, Delphine De Sutter, Kris Gevaert, Francis Impens, Ilkka Miinalainen, Pieter-Jan Van Bockstal, Thomas De Beer, Marca H.M. Wauben, Esther N.M. Nolte-'t-Hoen, Katarzyna Bloch, Johannes V. Swinnen, Edwin van der Pol, Rienk Nieuwland, Geert Braems, Nico Callewaert, Pieter Mestdagh, Jo Vandesompele, Hannelore Denys, Sven Eyckerman et al.
Nature Communications 10 (1), 1-2 (2019)

2018

160 Human bone marrow contains high levels of extracellular vesicles in a tissue-specific subtype distribution (pdf, 1 MB)
Andreas Rank, Rienk Nieuwland, Anton Köhler, Cordula Franz, Johanna Waidhauser, and Bettina Toth
Plos One 13 (12), 1-11 (2018)
159 Essentials of extracellular vesicles: posters on basic and clinical aspects of extracellular vesicles (pdf, <1 MB)
Rienk Nieuwland, Juan Manuel Falcon-Perez, Carolina Soekmadji, Eric Boilard, Dave Carter, and Edit I. Buzas
Journal of Extracellular Vesicles 7 (1), 1548234 (2018)
158 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines (pdf, 1 MB)
Clotilde Théry, Kenneth W. Witwer, Elena Aikawa, Maria Jose Alcaraz, Johnathon D. Anderson, Ramaroson Andriantsitohaina, Anna Antoniou, Tanina Arab, Fabienne Archer, Georgia K. Atkin-Smith, D. Craig Ayre, Jean-Marie Bach, Daniel Bachurski, Hossein Baharvand, Leonora Balaj, Shawn Baldacchino, Natalie N. Bauer, Amy A. Baxter, Mary Bebawy, Carla Beckham, Apolonija Bedina Zavec, Abderrahim Benmoussa, Anna C. Berardi, Paolo Bergese, Ewa Bielska et al.
Journal of Extracellular Vesicles 7 (1), 1535750 (2018)
157 Tissue Factor Coagulant Activity is Regulated by the Plasma Membrane Microenvironment (pdf, <1 MB)
Yuanjie Yu, Anita N. Boïng, Chi M. Hau, Najat Hajji, Wolfram Ruf, Auguste Sturk, and Rienk Nieuwland
Thrombosis and Haemostasis 118 (06), 990-1000 (2018)
156 Extracellular vesicles from human saliva promote hemostasis by delivering coagulant tissue factor to activated platelets (pdf, 1 MB)
Y. Yu, E. Gool, R.J. Berckmans, F.A.W. Coumans, A.D. Barendrecht, C. Maas, N.N. van der Wel, P. Altevogt, A. Sturk, and R. Nieuwland
Journal of Thrombosis and Haemostasis 16 (6), 1153-1163 (2018)
155 Extracellular vesicles exposing tissue factor for the prediction of venous thromboembolism in patients with cancer: A prospective cohort study (pdf, <1 MB)
Nick van Es, Yohei Hisada, Marcello Di Nisio, Gabriela Cesarman, Ankie Kleinjan, Isabelle Mahé, Hans-Martin Otten, Pieter W. Kamphuisen, René J. Berckmans, Harry R. Büller, Nigel Mackman, and Rienk Nieuwland
Thrombosis Research 166, 54-59 (2018)
154 Transfusion of autologous extracellular vesicles from stored red blood cells does not affect coagulation in a model of human endotoxemia (pdf, 1 MB)
Anna L. Peters, Alexander P.J. Vlaar, Robin van Bruggen, Dirk de Korte, Joost C.M. Meijers, Rienk Nieuwland, and Nicole P. Juffermans
Transfusion 58 (6), 1486-1493 (2018)
153 Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017 (pdf, <1 MB)
A. Clayton, D. Buschmann, J.B. Byrd, D.R.F. Carter, L. Cheng, C. Compton, G. Daaboul, A. Devitt, J.M. Falcon-Perez, C. Gardiner, D. Gustafson, P. Harrison, C. Helmbrecht, A. Hendrix, A. Hill, A. Hoffman, J.C. Jones, R. Kalluri, J. Yoon Kang, B. Kirchner, C. Lässer, C. Lawson, M. Lenassi, C. Levin, A. Llorente et al.
Journal of Extracellular Vesicles 7 (1), 1473707 (2018)
152 Helium alters the cytoskeleton and decreases permeability in endothelial cells cultured in vitro through a pathway involving Caveolin-1 (pdf, 5 MB)
Kirsten F. Smit, Moritz Konkel, Raphaela Kerindongo, Maximilian A. Landau, Coert J. Zuurbier, Markus W. Hollmann, Benedikt Preckel, Rienk Nieuwland, Martin Albrecht, and Nina C. Weber
Scientific Reports 8 (4768), (2018)
151 Development of peritoneal carcinomatosis in epithelial ovarian cancer: a review (pdf, 9 MB)
Juliette O.A.M. van Baal, Cornelis J.F. van Noorden, Rienk Nieuwland, Koen K. van de Vijver, Auguste Sturk, Willemien J. van Driel, Gemma G. Kenter, and Christianne A.R. Lok
Journal of Histochemistry & Cytochemistry 66 (2), 67-83 (2018)
150 Detailed analysis of the plasma extracellular vesicle proteome after sepraration from lipoproteins (pdf, 5 MB)
Nasibeh Karimi, Aleksander Cvjetkovic, Su C. Jang, Rosella Crescitelli, Mohammad Ali Hosseinpour Feizi, Rienk Nieuwland, Jan Lötvall, and Cecilia Lässer
Cellular and Moleclular Life Sciences 75 (15), 2873-2886 (2018)
149 Centrifugation affects the purity of liquid biopsy-based tumor biomarkers (pdf, <1 MB)
Linda G. Rikkert, Edwin van der Pol, Ton G. van Leeuwen, Rienk Nieuwland, and Frank A.W. Coumans
Cytometry Part A 93 (12), 1207-12 (2018)
148 Extracellular vesicles in post-infarct ventricular remodelling (pdf, 1 MB)
Aleksandra Gąsecka, Edwin van der Pol, Rienk Nieuwland, and Ewa Stępień
Kardiologia Polska 76 (1), 69-6 (2018)
147 Deriving extracellular vesicle size from scatter intensities measured by flow cytometry (pdf, <1 MB)
Leonie de Rond, Frank A.W. Coumans, Rienk Nieuwland, Ton G. van Leeuwen, and Edwin van der Pol
Current Protocols in Cytometry 86 (1), e43 (2018)
146 Hollow organosilica beads as reference particles for optical detection of extracellular vesicles (pdf, 1 MB)
Zoltán Varga, Edwin van der Pol, Marcell Pálmai, Raul Garcia-Diez, Christian Gollwitzer, Michael Krumrey, Jean-Luc Fraikin, Aleksandra Gasecka, Najat Hajji, Ton G. van Leeuwen, and Rienk Nieuwland
Journal of Thrombosis and Haemostasis 16 (8), 1646-55 (2018)
145 Absolute sizing and label-free identification of extracellular vesicles by flow cytometry (pdf, 1 MB)
Edwin van der Pol, Leonie de Rond, Frank A.W. Coumans, Elmar L. Gool, Anita N. Böing, Auguste Sturk, Rienk Nieuwland, and Ton G. van Leeuwen
Nanomedicine: Nanotechnology, Biology and Medicine 14 (3), 801-10 (2018)
144 Comparison of generic fluorescent markers for detection of extracellular vesicles by flow cytometry (pdf, <1 MB)
Leonie de Rond, Edwin van der Pol, Chi M. Hau, Zoltan Varga, Auguste Sturk, Ton G. van Leeuwen, Rienk Nieuwland, and Frank A.W. Coumans
Clinical Chemistry 64 (4), 680-9 (2018)
143 Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation (pdf, 1 MB)
Edwin van der Pol, Auguste Sturk, Ton van Leeuwen, Rienk Nieuwland, Frank Coumans, and STH-SSC-VB Working Group
Journal of Thrombosis and Haemostasis 16 (6), 1236-45 (2018)

2017

142 Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility (pdf, 2 MB)
Kenneth W. Witwer, Carolina Soekmadji, Andrew F. Hill, Marca H. Wauben, Edit I. Buzás, Dolores Di Vizio, Juan M. Falcon-Perez, Chris Gardiner, Fred Hochberg, Igor V. Kurochkin, Jan Lötvall, Suresh Mathivanan, Rienk Nieuwland, Susmita Sahoo, Hidetoshi Tahara, Ana C. Torrecilhas, Alissa M. Weaver, Hang Yin, Lei Zheng, Yong S. Gho, Peter Quesenberry, and Clotilde Théry
Journal of Extracellular Vesicles 6 (1), 1396823 (2017)
141 Surface Plasmon Resonance is an Analytically Sensitive Method for Antigen Profiling of Extracellular Vesicles (pdf, 2 MB)
Elmar L. Gool, Ivan Stojanovic, Richard B.M. Schasfoort, Auguste Sturk, Ton G. van Leeuwen, Rienk Nieuwland, Leon W.M.M. Terstappen, and Frank A.W. Coumans
Clinical Chemistry 63 (10), 1633-1641 (2017)
140 Comparison of risk prediction scores for venous thromboembolism in cancer patients: a prospective cohort study (pdf, <1 MB)
Nick van Es, Marcello Di Nisio, Gabriela Cesarman, Ankie Kleinjan, Hans-Martin Otten, Isabelle Mahé, Ineke T. Wilts, Desirée C. Twint, Ettore Porreca, Oscar Arrieta, Alain Stépanian, Kirsten Smit, Michele De Tursi, Suzanne M. Bleker, Patrick M. Bossuyt, Rienk Nieuwland, Pieter W. Kamphuisen, and Harry R. Büller
Haematologica 102 (9), 1494-1501 (2017)
139 The ability of extracellular vesicles to induce a pro-inflammatory host response (pdf, <1 MB)
Maike E. van Hezel, Rienk Nieuwland, Robin van Bruggen, and Nicole P. Juffermans
International Journal of Molecular Sciences 18 (6), 1285 (2017)
138 Microvesicles in vascular homeostasis and diseases (pdf, 1 MB)
Victoria C. Ridger, Chantal M. Boulanger, Anne Angelillo-Scherrer, Lina Badimon, Olivier Blanc-Brude, Marie-Luce Bochaton-Piallat, Eric Boilard, Edit I. Buzas, Andreas Caporali, Francoise Dignat-George, Paul C. Evans, Romaric Lacroix, Esther Lutgens, Daniel F.J. Ketelhuth, Rienk Nieuwland, Florence Toti, Jose Tuñon, Christian Weber, and Imo E. Hoefer
Thrombosis Haemostasis 117 (07), 1296-1316 (2017)
137 Platelet extracellular vesicles as biomarkers for arterial thrombosis (pdf, 1 MB)
Aleksandra Gasecka, Anita N. Böing, Krzysztof J. Filipiak, and Rienk Nieuwland
Platelets 28 (3), 228-234 (2017)
136 Bulk immunoassays for analysis of extracellular vesicles (pdf, 1 MB)
Frank A.W. Coumans, Elmar L. Gool, and Rienk Nieuwland
Platelets 28 (3), 242-248 (2017)
135 The histophysiology and pathophysiology of the peritoneum (pdf, 3 MB)
J.O.A.M. Van Baal, K.K. Van de Vijver, R. Nieuwland, C.J.F. Van Noorden, W.J. Van Driel, A. Sturk, G.G. Kenter, L.G. Rikkert, and C.A.R. Lok
Tissue and Cell 49 (1), 95-105 (2017)
134 Dimensional characterization of extracellular vesicles using atomic force microscopy (pdf, 1 MB)
N. Sebaihi, B. De Boeck, Y. Yuana, R. Nieuwland, and J. Pétry
Measurement Science and Technology 28 (3), 034006 (2017)
133 Standardization of microparticle enumeration across different flow cytometry platforms: results of a multicenter collaborative workshop (pdf, <1 MB)
S. Cointe, C. Judicone, S. Robert, M.J. Mooberry, P. Poncelet, M. Wauben, R. Nieuwland, N.S. Key, F. Dignat-George, and R. Lacroix
Journal of Thrombosis and Haemostasis 15 (1), 187-193 (2017)
132 From platelet dust to gold dust: physiological importance and detection of platelet microvesicles (pdf, <1 MB)
Edwin van der Pol, and Paul Harrison
Platelets 28 (3), 211-3 (2017)
131 Methodological guidelines to study extracellular vesicles (pdf, 1 MB)
Frank A.W. Coumans, Alain R. Brisson, Edit I. Buzas, Françoise Dignat-George, Esther E.E. Drees, Samir El-Andaloussi, Costanza Emanueli, Aleksandra Gasecka, An Hendrix, Andrew F. Hill, Romaric Lacroix, Yi Lee, Ton G. van Leeuwen, Nigel Mackman, Imre Mäger, John P. Nolan, Edwin van der Pol, D. Michiel Pegtel, Susmita Sahoo, Pia R.M. Siljander, Guus Sturk, Olivier de Wever, and Rienk Nieuwland
Circulation Research 120 (10), 1632-48 (2017)
130 Biological reference materials for extracellular vesicle studies (pdf, 2 MB)
Sami Valkonen, Edwin van der Pol, Anita Böing, Yuana Yuana, Marjo Yliperttula, Rienk Nieuwland, Saara Laitinen, and Pia R.M. Siljander
European Journal of Pharmaceutical Sciences 98, 4-6 (2017)

2016

129 Monocyte-mediated activation of endothelial cells occurs only after binding to extracellular vesicles from red blood cell products, a process mediated by beta-integrin (pdf, <1 MB)
Marleen Straat, Maike E. van Hezel, Anita Böing, Anita Tuip-De Boer, Nina Weber, Rienk Nieuwland, Robin van Bruggen, and Nicole P. Juffermans
Transfusion 56 (12), 3012-3020 (2016)
128 Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients (pdf, 1 MB)
M.A.J. van Eijndhoven, J.M. Zijlstra, N.J. Groenewegen, E.E.E. Drees, S. van Niele, S.R. Baglio, D. Koppers-Lalic, H. van der Voorn, S.F.W.M. Libregts, M.H.M. Wauben, R.X. de Menezes, J.R.T. van Weering, Rienk Nieuwland, L. Visser, A. van den Berg, D. de Jong, and D.M. Pegtel
JCI Insight 1 (19), e89631 (2016)
127 Extracellular vesicles in human follicular fluid do not promote coagulation (pdf, 1 MB)
Cordula Franz, Anita N. Böing, Markus Montag, Thomas Strowitzki, Udo R. Markert, Sebastiaan Mastenbroek, Rienk Nieuwland, and Bettina Toth
Reproductive Biomedicine Online 33 (5), 652-655 (2016)